24.07.2024
SwissPedHealth's protocol paper provides an overview of the study's aim to transform paediatric healthcare by developing a sustainable, data-driven infrastructure in Swiss hospitals to standardise and enhance the use of clinical data for research, quality assurance, and policy-making.
06.12.2023
The Swiss Personalized Health Network (SPHN) has developed a new genomics extension for the SPHN RDF Schema, enhancing the integration and FAIRification of omics data. This advancement, achieved in collaboration with SwissPedHealth and other experts, extends the SPHN Semantic Interoperability Framework beyond clinical data, encompassing genomic experiments and metadata. The extension promotes seamless data sharing and reuse across the Swiss healthcare sector, solidifying SPHN's commitment to advancing personalized health research.
25.01.2024
A groundbreaking study led by the
Kinderspital Zürich,
employing artificial intelligence to analyze data from over 3.5 million children, has resulted in the development of the Phoenix Sepsis Score. This new tool provides a reliable method for diagnosing sepsis in children, which could significantly enhance early detection and treatment of this potentially fatal condition. The research, recognized for its global impact, has been published in
JAMA
and supports efforts to combat sepsis worldwide, and the
national program for quality improvement in sepsis.
26.01.2023
Combining the results of multiple molecular analyses could lead to improved diagnosis of the rare and severe hereditary metabolic disease, methylmalonic aciduria. The new research offers potential benefits for affected individuals and could also pave the way for improved treatment options in the future.
26.01.2023
Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency. Nature Metabolism, 26 January 2023, doi:
10.1038/s42255-022-00720-8.
Forny P, Bonilla X, Lamparter D, Shao W, Plessl T, Frei C, Bingisser A, Goetze S, van Drogen A, Harshman K, Pedrioli PGA, Howald C, Poms M, Traversi F, Buerer C, Cherkaoui S, Morscher RJ, Simmons L, Forny M, Ioannis Xenarios, Aebersold R, Zamboni N, Rätsch G, Dermitzakis E, Wollscheid B, Matthias R. Baumgartner MR, Froese DS.
